Endocrine Abstracts

Introduction: Wolfram syndrome (WS) is a genetic disorder that affects the quality of life of very young Patients. This condition is also referred to as DIDMOAD (diabetes insipidus-diabetes mellitus-optic atrophy-deafness).characterized by non immunogenic diabetes mellitus, and a progressive atrophy of the optic nerve, which occurs generally in the first decade of life.In order to prevent and treat this condition, a better understanding of WS pathogenesi...